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2006-2008 Research Projects: Emerging Technologies

Project: Development of cDNA Micro-assays for Analysis of Environmental Stressors and Disease in Local Populations of Atlantic White Shrimp, Litopenaeus setiferus

Principal Investigators

Dr. Paul Gross and Dr. Jonas Almeida, Medical University of South Carolina

Research Description

This continuing proposal will further their efforts on the development of cDNA micro-arrays as a tool for analyzing environmental stressors and disease. These arrays are a new and relatively untested technology. The proposed research will apply this new technology to local populations of the commercially important species of white shrimp, Litopenaeus setiferus, which is a keystone species in South Carolina estuarine systems.

Two key objectives of the project are to: (1) collect and analyze functional genomic data to understand their physiological interaction with the environment using bioinformatic-based approaches; and (2) train new researchers, particularly graduate students, in the new and emerging technologies associated with “eco-genomics.” After the initial year, three graduate students in the Medical University of South Carolina’s Marine Biomedicine and Environmental Science Program have been successfully trained in the use of “eco-genomics” technologies.

Contact for Questions

Paul Gross ( or Jonas Almeida (